Soft Tissue Tumors

GENERAL INFORMATION Tumoral calcinosis is a very rare entity, characterized by large tumorlike calcium deposits and painless mass, arising near to the articular soft tissue areas. Common areas affected are elbows, hips, knees rarely involve hands and feet. No obvious...

GENERAL INFORMATION Synovial sarcoma is a common soft tissue malignancy accounting for 5 – 10 % of soft tissue sarcomas. Patients with synovial cell sarcoma are often between the ages of 15 and 35 years old; generally younger than patients with other types of soft...

Synovial chondromatosis is an uncommon, benign, process that occurs in large joints, such as the knee (50%), hip, elbow, or shoulder. This process mainly affects synovium and hence most commonly arises from joints and tendons which are lined by synovium. Synovial...

GENERAL INFORMATION Solitary fibrous tumor is a rare and usually benign mesenchymal tumor, composed of thick collagen and characteristically has a prominent haemangiopericytoma-like branching vascular pattern. Solitary fibrous tumors usually affect adult group (median...

GENERAL INFORMATION Rhabdomyosarcoma is a malignant soft tissue tumor (sarcoma) originating from striated skeletal muscle. Although rare,  it is one of the more common solid cancerous tumors (sarcoma) affecting children.  This entity occurs with same...

GENERAL INFORMATION Pigmented villonodular synovitis (PVNS) is described as a benign villous or nodular proliferation of synovium. Pigmented villonodular synovitis occurs commonly in the third and fourth decades of life. Also known as diffuse tenosynovial giant cell...

GENERAL INFORMATION • Benign soft tissue tumor arising from a peripheral nerve sheath (epineurium) derived from a schwann cell.  • Also known as Neurilemoma• Arises from the periphery of the nerve, epineurium • The nerve is displaced eccentrically• Small...

Proliferative myositis is an intramuscular reactive process. It is identical in appearance to proliferative fasciitis, except its locations is within skeletal muscle. Patients usually present with a painless mass on the upper arm or trunk. This disease is cured by...

Plantar fibromatosis is a type of superficial fibromatosis that affects the plantar aspect of the foot and its subcutaneous fat. One third of patients diagnosed with this disease are younger than 30 years of age and children may occasionally be affected. Usually...

Nodular fasciitis is a reactive process that can occur in patients of all ages, but most commonly occurs between 20-40 years of age. While it can occur within any site of the body, the upper extremities--especially the forearms--are the most frequent site involved....

GENERAL INFORMATION Myositis ossificans is a benign intramuscular mass usually caused by an injury. It can form directly in a muscle or form closely applied to the surface of a bone. Also called benign fibro-osseous lesion or heterotopic ossification is composed of...

Myobroma is a pediatric type of tumor. It may arise in one area or occur in multiple sites. It contains nodules of spindle cells that appear to be related to smooth muscle and less differentiated cells that are small, round, and basophilic. These are rare tumors and...

GENERAL INFORMATION Malignant peripheral nerve sheath tumor (MPNST) is a malignant form of the schwannoma. It is a spindle cell sarcoma that can arise from a neurofibroma and shows nerve sheath differentiation.  CLINICAL DATA Associated with neurofibromatosis 1...

GENERAL INFORMATION Lymphangioma is a benign vascular lesion. It is believed to originate from a non communication between the lymphatics and venous system. CLINICAL DATA • A benign vascular lesions• Appear to show lymphatic differentiation• Thin-walled...

GENERAL INFORMATION Low Grade Fibromyxoid Sarcoma (LGFS) is a low grade sarcoma with fibrous and myxoid areas. More frequent in young to middle age patients with slight male predominanc.  CLINICAL DATA The trunk and deep soft tissues of the lower extremities are...

GENERAL INFORMATION Liposarcoma is one of the most commonly diagnosed soft tissue sarcomas, accounting for approximately 12.8% of all sarcomas. Most patients are older than 50 years of age and most patients complain of a large,...

GENERAL INFORMATION Pleomorphic sarcoma is a high grade sarcoma of lipogenic (fatty/adipose) origin. It is a type of liposarcoma that has some lipoblasts  admixed with mostly high grade pleomorphic appearing spindle cells.  CLINICAL DATA Represents 5 to 10%...

GENERAL INFORMATION Liposarcoma is one of the most commonly diagnosed soft tissue sarcomas, accounting for approximately 12.8% of all sarcomas. Most patients are older than 50 years of age who complain of a large, painless, deep-seated mass located proximally in the...

GENERAL INFORMATION Liposarcoma is one of the most commonly diagnosed soft tissue sarcoma, accounting for approximately 12.8% of all sarcomas. Most patients are older than 50 years of age who complain of a large, painless, deep-seated mass located...

GENERAL INFORMATION Benign tumor composed of mature adipocytes with uniform nuclei identical to the cells of normal adult fat. Lipoma is the most common tumor of soft tissue. Benign/Mature adipocytes have cytoplasmic lipid in a single large vacuole that pushes the...

GENERAL INFORMATION Leimyosarcoma is a rare malignant spindle cell tumor (sarcoma) composed of cells which demonstrate smooth muscle differentiation. Almost 50% percent affect the retroperitoneum. Leiomyosarcoma have been subdivided into 3 categories: leiomyosarcoma...

This is a type of fibromatosis that typically affects children less than five years of age. Patients are usually brought to a physician's attention because of the discovery of a large mass. The most common sites of involvement are the shoulder irdle and muscles and...

This is a hereditary condition that usually manifests itself in early childhood. It consists of cutaneous and subcutaneous tumors composed of nodules of fibroblasts in a hyalinized, collagenized stroma. It is a rare condition, and patients usually present with...

GENERAL INFORMATION Hibernoma is a benign neoplasm made up of multivacuolated brown fat cells. It is a type of lipoma. CLINICAL DATA • Rare, represents less than 2% of all types of  lipomas• Made of brown fat• Affects ages between second and third...

GENERAL INFORMATION Giant cell tumor of tendon sheath is defined as a benign reactive lesion which is similar to PVNS. Giant cell tumor of tendon sheath is also named  tenosynovial giant cell tumor. GCT of tendon sheath is a circumscribed tumor that does not...

This is a pediatric, benign, subcutaneous soft tissue tumor that affects children in their first ten years of life. It primarily involves the axilla, as well as the upper arm and shoulder, thigh, inguinal area, back and forearm. It usually presents as a painless...

GENERAL INFORMATION A fibrosarcoma is a malignant (cancerous) spindle cell neoplasm originating  from fibroblasts that shows no other evidence of differentiation.  The spindle cells are usually uniform and show minimal pleomorphism depending on the grade of...

Fibroma of tendon sheath is a circumscribed, often multinodular, tumor that occurs in the extremities and most often affects the hands, fingers and wrists. It affects all ages of patients but is most commonly reported in adults. It grows very slowly and may be present...

Deep fibromatoses include extraabdominal fibromatosis, or extraabdominal desmoid tumors. The deep fibromatoses are tumors that have the capacity for infiltration and recurrence. The are locally aggressive in nature and may be uncontrollable. They do not metastasize....

GENERAL INFORMATION Extraskeletal Ewing Sarcoma (EES) is a malignant small round-blue cell tumor than arises most often in Children and adolescents. Tefft et al in 1969 described the first series of Extraskeletal Ewing Sarcoma that arose from the...

GENERAL INFORMATION Extraskeletal chondrosarcoma is a rare cancerous soft tissue tumor. It is a cartilaginous producing spindle cell tumor (sarcoma) that occurs in the soft tissues as opposed to the more typical site in bone.  Represents up to 2% of all soft...

Elastofibroma is an actual reactive process that presents itself as a tumor. It is fibrous in nature and almost exclusively affects the soft tissues around the scapula. It has been suggested that elastofibromas fevelop as a response to repeated trauma. One-third of...

GENERAL INFORMATION Dermatofibrosarcoma Protuberans (DFSP) is an infrequent type of malignant skin sarcoma. It arises from the dermis of the skin. DFSP accounts for less than 6% of all soft tissue sarcomas. There are approximately 1000 cases in the United States...

GENERAL INFORMATION Clear Cell Sarcoma of Soft tissue is a very rare (1% of all soft tissue sarcomas) and aggressive melanocytic sarcoma that was described for the first time by Enzinger in 1965. It is also referred to as melanoma of soft parts. CLINICAL DATA It is...

This is a fibroblastic lesion that typically affects children. It consists of large numbers of fibroblasts that form around nodules of calcium or cartilage. Rarely, bone may be present. This is a very uncommon tumor. Almost all calcifying fbromas occur in the hands...

GENERAL INFORMATION Angiosarcoma is a rare malignant neoplasm that arises from endothelial cells of blood vessels. Very rare in infant and young adults but has a very poor prognosis. It most typically arises in the setting of chronic lymphedema often caused by...

Angiolipoma is a subcutaneous benign tumor, made up of mature fat and blood vessels that often presents as multiple lesions.  It sometimes arises intramuscularly. The incidence may be associated with familial heritage, close to 5% of the cases.  Angiolipomas often...