bone tumors, dr james c wittig, othopedic oncologist, new york, new jersey
Patient Education
Classification/Bone Tumors
General Type Benign Entity Malignant Entity
Osseous Producing Benign Osseous Malignant Osseous
Osteosarcoma (OS)

(Bone Producing)
(Osteoid Producing)

Osteoma
Osteoid Osteoma
Osteoblastoma

Intramedullary Types
Conventional OS
(Most Common)
Telangiectatic OS
Low Grade Intraosseous OS

Intracortical OS
Cartilage Producing Benign Chondroid Malignant Chondroid
Chondrosarcoma (CS)
(Chondriod Producing) Enchondroma
Osteochondroma
Periosteal Chondroma
Chondroblastoma
Chondromyxofibroma (CMF)
Multiple Hereditary Exostoses (MHE) Enchondromatosis
Mafucciâs Syndrome
Intramedullary
Conventional CS
Grade 1
Grade 2
Grade 3
Clear Cell CS
Mesenchymal CS
Dedifferentiated CS
Juxtacortical/Surface
Periosteal CS
Secondary CS
Osteochondroma
Enchondroma
MHE
Enchondromatosis
Mafucci’s Syndrome
Fibrous Producing Benign Fibrous Malignant Fibrous
(Fibrous Tissue Producing) Nonossifying Fibroma
Fibrous Dysplasia
Desmoplastic Fibroma
Benign Fibrous Histiocytoma
Ossifying Fibroma
Fibrosarcoma
Grade 1 (Low Grade)
Grade 2 (Intermediate)
Grade 3 (High Grade)

Malignant Fibrous Histiocytoma
(MFH)

(aka: Myxoid Fibrosarcoma)
Small Round Blue Cell Beningn Small Round Blue Cell Malignant Small Round Blue Cell
(These tumors do not produce matrix; Non Matrix Producing) Eosinophilic Granuloma (EG)
(Infection can mimic a Small Round Blue Cell Tumor)
Ewing Sarcoma / PNET
Lymphoma
Myeloma
Vascular Origin Benign Vascular Malignant Vascular
(Blood Vessel Origin) Hemangioma
Lymphangioma
Hemangioendothelioma
Hemangiopericytoma
Angiosarcoma
Giant Cell Benign Giant Cell Malignant Giant Cell
  Giant Cell Tumor (GCT)
Aneurysmal Bone Cyst
(ABC)

Malignant Giant Cell Tumor
Muscle Origin Benign Muscle Malignant Muscle
    Leiomyosarcoma
Rhabdomyosarcoma
Neurogenic Benign Nervous Malignant Nervous
(Nerve origin; Very rare to occur in bone) Schwannoma
(aka: Neurilemoma)
Malignant Peripheral Nerve
Sheath Tumor (MPNST)

(aka: Neurofibrosarcoma)
Fat Producing Benign Fatty Malignant Fatty
  Lipoma Liposarcoma
Miscellaneous Origin/
Unknown Origin
Benign Malignant
  Ganglion
Unicameral/Simple Bone Cyst (UBC)
Aneurysmal Bone Cyst
(ABC)

Liposclerosing Myxofibrous-
Tumor (LSMFT)
Adamantinoma
Synovial Sarcoma
Pediatric Bone Tumors Benign Malignant/Sarcomas
  Aneurysmal Bone Cyst (ABC)
Chondroblastoma
Enchondroma
Enchondromatosis
Eosinophilic Granuloma
Fibrous Dysplasia
Hemangioma
Nonossifying Fibroma
Osteoblastoma
Osteochondroma
Osteoid Osteoma
Ossifying Fibroma
Periosteal Chondroma
Ewing Sarcoma
Lymphoma
Osteosarcoma
Primitive Neuro- ectodermal Tumor (PNET)
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